• Start date:
  • 15 April 2020
  • Duration:
  • 3 days
  • Working as:
  • (Academic) researcher, PhD


The Leiden University Medical Center finds it extremely important to protect its patients and employees against the risk of spreading the corona virus (SARS-CoV-2). Our patients are often very vulnerable and our staff can’t be missed: continuity of care is essential for us. The decision has been made to cancel this course due to the coronavirus and we realize that cancelling this course has a great impact. We have informed the participants and speaker personally about this cancellation.


This course will give a broad overview of topics in meta-analysis. Most standard topics in meta-analysis will be covered, such as risk of bias analysis, searching studies, fixed versus random effect models, heterogeneity, publication bias, differences between meta-analysis of randomized trials and meta-analysis observational studies. In practical sessions (STATA, no pre-knowledge required) students will perform a standard meta-analysis by themselves. The course will briefly cover some more advanced topics (bivariate meta-analysis, combining different metrics, network analysis).

Program Meta-analyse (draft)

  Wednesday 15 April 2020                          
08.30 Registration
09:00 Introduction to the course
Dr. Olaf Dekkers
09:10 Meta-analysis: Why &how?
Dr. Olaf Dekkers
10:15 Break
10:30 The statistical approach
Dr. Marta Fiocco
11:30 Heterogeneity and Risk of bias
Dr. Olaf Dekkers
12:30 Break and lunch
13:00 Searching for literature: potentials and pitfalls
Karin van der Hoorn (Geb-1 J1-84)
15:15 Pooling effect estimates I
Prof. dr. Saskia le Cessie
  Thursday 16 April 2020                        
08:45 Registration    
09:00 Publication bias
Dr. Olaf Dekkers
09:30 Heterogeneity: statistical
Dr. Marta Fiocco
10:30 Break
10:45 Publication bias: statistical
Dr. Marta Fiocco
12:00 Break and lunch
12:45 Practical session: risk of bias analysis
Dr. Olaf Dekkers
13:45 Meta-analysis of observational studies
Dr. Olaf Dekkers
14:45 Break
15:00 Pooling different effect measures
Dr. Olaf Dekkers
  Friday 17 April 2020                           
08:45 Registration
09:00 Pooling effect estimates II
Prof. dr. Saskia le Cessie
10:00 Break
10:15 Practical in STATA I
Prof. dr. Saskia le Cessie
12:00 Break and lunch
12:30 Practical in STATA II
Prof. dr. Saskia le Cessie en Katarina Papadimitropoulou
13:45 Tips and tricks for data-extraction
Prof. dr. Saskia le Cessie
14:30 Break
14:45 Meta-analysis of diagnostical studies
Prof. dr. Saskia le Cessie
15:45 Final remarks
Albinusdreef 2, 2333 ZA Leiden

Participation fee: € 550,-

Participation fee LUMC employees/PhD students: € 150,-

The course is free of charge for students of the Leiden University. Make sure that you mention your student number.